mouse pancreas tissue were subjected to SDS PAGE followed by western blot with FNab01838(COL3A1 antibody) at dilution of 1:500
IP Result of anti-Collagen Type III (N-terminal) (IP:FNab01838, 4ug; Detection:FNab01838 1:500) with mouse skin tissue lysate 3200ug.
Immunohistochemistry of paraffin-embedded human hepatocirrhosis tissue slide using FNab01838(COL3A1 Antibody) at dilution of 1:100
Background
Type III collagen is a fibrillar forming collagen comprising three a1(III) chains and is expressed in early embryos and throughout embryogenesis. In the adult, type III collagen is a major component of the extracellular matrix in a variety of internal organs and skin. It occurs in most soft connective tissues along with type I collagen. COL3A1 gene encodes type III procollagen. Mutations in this gene are associated with type III and IV Ehlers-Danlos syndrome, and with aortic and arterial aneurysms.(PMID: 9050868; 2445760)